Dr. Gonzalez wrote an eight part article series for Natural Health 365 on the history and failure of the ketogenic diet for cancer. Dr. Gonzalez’s nutritional cancer treatment expertise is much deeper than ANYONE currently promoting the ketogenic diet for cancer, because unlike anyone else promoting it, he actually treats cancer patients with nutrition every day.
The digestion of carbohydrates (sugar and starch) releases sugar (glucose) into the bloodstream. Greater carb intake results in rising blood sugar and insulin, a pancreatic hormone that manages blood sugar. Going keto replaces dietary carb with fat and protein. Over time, your cells switch metabolic pathways, and burn stored and dietary fat as a primary energy source instead of sugar. As more fat is burned, some of it is converted into ketone bodies. As blood glucose and insulin levels fall, and ketone levels rise, your muscles (skeletal and heart), use the fats in the bloodstream as fuel, while your brain uses the ketones. The result is more energy, clearer thinking and better health. Ketones are beneficial in many different ways, and being in this metabolic state of "nutritional ketosis" (where blood sugar is low and ketone levels are moderate) has some powerful effects on your metabolism. There is strong research evidence that these metabolic-affecting diets can be used to treat the following medical conditions:
Although studies have shown that the keto diet can reduce seizures for children with epilepsy, there is no evidence indicating that keto helps with other brain disorders or improves mental cognition, according to Harvard Health Publishing. Some studies show that keto may lower blood sugar for people with type 2 diabetes, but there is not enough long-term research to determine whether it’s safe and effective for diabetics.
[1:53] – Explaining the concept of “hyper-responder”. Dave talks about his own experiences after discovering he was pre-diabetic and switching to the low carb, ketogenic diet. Are there concerns about the possibility of high cholesterol with this diet? For most people, there is a very small change in cholesterol levels. However, after 7 months on a keto diet Dave found he suddenly had a very high increase in his cholesterol scores.
The body needs bile to break down and digest dietary fat, and the gallbladder is responsible for storing bile before its release into the small intestine. Removal of the gallbladder and gallbladder disease cause fat malabsorption and may make it difficult to follow a ketogenic diet. If you have had your gallbladder removed or have existing gallbladder disease, consult with your doctor before trying a ketogenic diet.
Today, you’ll see ketogenic diets promoted to prevent disease, increase energy, boost physical and mental performance, and so much more. But let’s face it: Most people want to try keto to lose weight. While that’s not a bad thing—you can lose weight doing it—ketogenic diets were never designed for weight loss, and done incorrectly, a side effect can actually make you gain weight.
Well, I am going to give this another try. I have great difficulty in eating greens , or drinking them, also I am not fond of fats, years and years of low fat diets have totally screwed my metabolism,and taste buds. I will read this page every day to keep my mind focused. Start tomorrow when I get up …… I work nights which can cause me problems as well. When I tried this diet before, I got terrible cramp, now I realise I wasn’t drinking enough water. Anyway.here goes.
What we haven’t talked about is what raised inflammation yet. It’s two main things. I call them the twin villains in your health. Number one is, not surprising coming out of my mouth, carbohydrates are dastardly, especially the refined ones. Grains, starches, sugars, they’re just bad news for you and avoid if at all possible because they’re going to raise your inflammation the most. The second one, a lot of my low carb, keto friends are still eating. It disappoints me Leanne, because I think they don’t realize the negative impact that they’re having. It’s in just about every packaged food, even the so called low carb, keto foods. That’s vegetable oils. You really have to eliminate Canola oil, soy bean oil, cotton seed oil, corn oil … I don’t care if the American Heart Association has their stupid heart health symbol on it, it’s not heart healthy. The reason it’s not heart healthy … I’ll tell you why it’s heart healthy in a minute, why they think it is.
The book summarizes, then enlarges upon, the concepts of Otto Warburg, MD, the great German scientist who won the Nobel Prize in Medicine and Physiology in 1931 for his work on cellular oxidation and energy production. No scientist has ever been nominated more frequently for the cherished Prize than Dr. Warburg, but he lost his chance for a second win, according to some sources, in 1944 after Hitler ordered that no German scientist could accept the award.
When in the hospital, glucose levels are checked several times daily and the patient is monitored for signs of symptomatic ketosis (which can be treated with a small quantity of orange juice). Lack of energy and lethargy are common, but disappear within two weeks. The parents attend classes over the first three full days, which cover nutrition, managing the diet, preparing meals, avoiding sugar, and handling illness. The level of parental education and commitment required is higher than with medication.
Ketogenic diets represent a far more effective strategy for managing type 2 diabetes than the American Diabetes Association’s high-carb, low-fat dietary guidelines. Unlike the ADA’s guidelines, a ketogenic diet significantly reduces blood sugar, hemoglobin A1c levels, waist circumference, and triglycerides in diabetic individuals. (13) Most importantly, research indicates that the diet is sustainable for diabetic patients and that the beneficial changes can be maintained over the long term. (14)
Unknown to most, even within the alternative world, my friend Bob Atkins tried the ketogenic diet for some 12 years on many of his cancer patients, with no significant success as he reported to me. As a telling point, under the name “Dr. Robert Atkins” on Amazon, one will find dozens of books he authored including his original diet book, its many incarnations and editions, along with books on vitamins, minerals – but glaringly absent, no book on cancer. Yes, the ketogenic diet has been tried before, with cancer patients, and without success.
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As individuals in general, we never hesitate to gorge on pounds of sugar with, before, and after every meal. Sugars and carbohydrates should rarely be included in our diets. One century ago, the average US citizen consumed 5 pounds of sugar per year; today, we consume an inconceivable average of 150 pounds per year. This becomes even more horrifying when we realize it only takes 100 grams of sugar to restrain our white blood cell’s ability to kill the bad cells in our body by 90% for several hours; this happens within 15 minutes of digestion. Founder of the American Anti-Cancer Institute (AACI), Bob Wright, adds, “One can of [soda] has enough sugar to shut down 50% of our immune system for a minimum of 4 hours.” When we consume sugar, we are simultaneously shutting off our defenses while pouring gasoline on the fire that is cancer. When we take into account that “50 to 70% of our total immune system cells cannot see cancer … even on our best day,” the notion of adding it to our diet seems even more blasphemous.
Just from researching that I have been doing, this information seems to make a lot of sense and I may have found some information that is pertinent as to why many of you have experienced a rise in LDL levels. VLDL become LDLs when they drop the triglyceride. So, as we consume less carbs we start to lose triglycerides and the VLDLs start to become LDLs. I am no professional by any means, but as I read that article it made sense as well. It takes a while for some people’s livers to start to get the picture and send out more HDL to round up the LDL and there are things that we can do to aid that process such as adding olive oil and coconut oil to our diets as well as eating purple produce and exercising, but the LDL count will probably rise at first and slowly drop from thereafter. It will probably drop faster if we are taking steps to raise our HDL. The longer our body (liver) has been exposed to an unhealthy diet, the longer it will take to recover from it.
Your child may start the diet in the hospital, so nurses and doctors can observe the first few days. Your child will probably need to go without any food for 36 to 48 hours before beginning the diet. After that, food is gradually increased over a few days. This diet does not provide all the vitamins a body needs, so your child will probably have to take sugar-free vitamin supplements.
How ketosis helps with epilepsy isn't known, but it does. Researchers at Johns Hopkins University studied 150 children with epilepsy in one important study. After a year on the ketogenic diet, half of children had 50% fewer seizures. One fourth of the children reduced their seizures by 90%. After a few years on the diet, many of these children no longer needed medications at all.
Before starting, ask yourself what is really realistic for you, Mattinson suggests. Then get your doctor’s okay. You may also work with a local registered dietitian nutritionist to limit potential nutrient deficiencies and talk about vitamin supplementation, as you won’t be eating whole grains, dairy, or fruit, and will eliminate many veggies. “A diet that eliminates entire food groups is a red flag to me. This isn’t something to take lightly or dive into headfirst with no medical supervision,” she says.
Collectively, these findings suggest that LDL particle size is a more precise indicator of future cardiovascular illness than total LDL cholesterol even when people have high levels of one but not the other. That being said, LDL-C is still a useful indicator for future cardiovascular illness and ideally you want to have both low LDL-C and LDL-P. (Click here to find optimal ranges for LDL-C and here for LDL-P)
Cyclical ketosis means you’re sometimes in ketosis and sometimes aren’t. A few days each week—the night before workout days to build glycogen stores in your muscles—try increasing your intake of berries, higher complex carb veggies (like sweet potatoes), and non-gluten grains. It might knock you out of ketosis temporarily, but it also provides a wealth of nutrients to keep you lean, healthy, and happy. This is also called flexible ketosis, which creates metabolic flexibility—the holy grail of metabolism management. I’ve also talked about cycling ketosis with intermittent fasting, which provides a win-win strategy to reach your health goals.
Ketogenesis has existed as long as humans have. If you eat a very low amount of carbohydrates, you starve your brain of glucose, its main fuel source. Your body still needs fuel to function, so it taps into your reserve of ketones, which are compounds the liver creates from fat when blood insulin is low. This process is known as ketosis: It’s like when a hybrid car runs out of gas and reverts to pure electricity.
To some ears, last week’s exultation over interleukin-2 has a familiar but discordant ring. Something similar happened about five years ago with a substance called interferon, the “magic bullet” of cancer research, featured on magazine covers and in articles with titles like “To Save Her Life – And Yours.” … But by 1984 the magic bullet had misfired; now the articles were called “The Myth of Interferon.”
Along with slashing carbs, a ketogenic plan also calls for limiting your protein consumption. If you know your macronutrients, you recognize that cutting carbs and restricting protein means seriously upping your fat intake. And that’s exactly what a true ketogenic diet entails. “You’d want healthy fats to account for about 80% of your calories, and protein around 20%,” Westman says. (For comparison’s sake, the average American gets roughly 50% of her calories from carbs, 15% from protein, and 30% from fat, per the CDC.)
What about fruits and vegetables? All fruits are rich in carbs, but you can have certain fruits (usually berries) in small portions. Vegetables (also rich in carbs) are restricted to leafy greens (such as kale, Swiss chard, spinach), cauliflower, broccoli, Brussels sprouts, asparagus, bell peppers, onions, garlic, mushrooms, cucumber, celery, and summer squashes. A cup of chopped broccoli has about six carbs.
Animal proteins (meat, fish, etc.) have very little, if any, carbs. You can consume them in moderate amounts as needed to control hunger. Overall, choose fattier cuts of meat rather than leaner ones. For example, chicken thighs and legs are preferable to chicken breasts because they contain much more fat. We’ve got quick keto diet chicken recipes to help.
In AD, ingestion of carbohydrates may worsen memory . Patients with cognitive impairment lacking the APO-ε4 allele (one of the risk factors for AD) showed improved scores on the Alzheimer Disease Assessment Scale–Cognitive Subscale after ingesting a medium-chain triglyceride shake, which induces low but measurable levels of ketosis [43, Class I]. Scores on this test for those with the APO-ε4 allele (as well as scores for all patients on some other tests administered in this study) were not improved after ingestion of the medium-chain triglyceride shake, making the generalizability of these findings to other patients with cognitive impairment (including AD) an area for further investigation.
However different these diets might be, each of these groups, and the many other traditional peoples Price studied, enjoyed excellent enduring health, free from the diseases of civilization – cancer, diabetes, heart disease, and hypertension. In his extraordinary and very detailed 1945 book Nutrition and Physical Degeneration, Dr. Price documented his thesis that we humans over the millennium adapted to and thrived on not one, as the experts usually claim, but a variety of different diets.
Recent findings Although most preclinical studies indicate a therapeutic potential for ketogenic diets in cancer treatment, it is now becoming clear that not all tumors might respond positively. Early clinical trials have investigated ketogenic diets as a monotherapy and – while showing the safety of the approach even in advanced cancer patients – largely failed to prove survival prolonging effects. However, it gradually became clear that the greatest potential for ketogenic diets is as adjuvant treatments combined with pro-oxidative or targeted therapies initiated in early stages of the disease. Beneficial effects on body composition and quality of life have also been found.
Taking your first step into the ketogenic diet is an exciting phase for your health. But before coming up with an actual ketogenic diet food list, it's important to first take a look at what you're eating now and take out anything that's unhealthy. This means that you have to remove sugars, grains, starches and packaged and processed foods from your diet. Basically, anything that won't add to your new eating regimen has to go. This is what I call a "pantry sweep."