If your child is helped by the diet and seizures are better controlled, your child may remain on the ketogenic diet for 2 to 3 years, or longer. The length of time on the diet will be determined by several factors, including how well the diet helps your child, whether your child can be weaned off seizure medications, and your willingness to continue the diet.
My latest blood work showed great HDL, VLDL, my LDL is just a bit high and my doc is saying we should do something about it. I don’t want to go on cholesterol meds they gave me leg cramps and other side effects I didn’t like. I think if he lets me give it more time that number could come down as well. I’ve lost 23lbs since January when I started Keto, my sugars are back to normal all other blood work is great! I’m going to try to add more of the avocado, coconut and olive oil and see what happens.
In 2005, he would eventually die with his dream of academic acceptance unrealized. But my colleague Dr. Linda Isaacs and I have worked diligently over the past 26 years, keeping the Kelley idea alive, that different people may require completely different diets. In the next installment, I will address my own experience treating patients diagnosed with advanced cancer with a Kelley based approach. Our therapy involves, oftentimes, diets high in carbohydrates, which proponents of the ketogenic diet would predict should fuel, not stop, cancer.

Since this is my full-time job, donations really help me keep afloat and allow me to post as much to the website as I do. I really appreciate any donation you want to give, but you can change the price yourself. I’ve added in $15 as the suggested price. I think that’s a very fair price considering other websites are charging in the hundreds of dollars, and I’ve seen what they are like on the inside.


2. I agree, progression of the score is now all that matters. Any concern with the NMR/other biomarker results, or am I a classic Lean Mass Hyperresponder, hyperabsorber? The literature is FILLED with studies showing raised TC/LDL on a fasting/ketogenic protocol. So is this simply physiological "view" and not an underlying fundamentally artherogenic profile?

Our bodies are incredibly adaptive to what you put into it – when you overload it with fats and take away carbohydrates, it will begin to burn ketones as the primary energy source. Optimal ketone levels offer many health, weight loss, physical and mental performance benefits.1There are scientifically-backed studies that show the advantage of a low-carb, ketogenic diet over a low-fat diet. One meta-analysis of low-carbohydrate diets showed a large advantage in weight loss. The New England Journal of Medicine study resulted in almost double the weight loss in a long-term study on ketone inducing diets.
I would receive further support for my thinking during the summer of 1981, after completing my second year of medical school. That July, through one of my journalism contacts from my previous life, I had the opportunity to meet the controversial alternative cancer practitioner, the dentist Dr. William Donald Kelley. Over a 20 year period beginning in the early 1960s, Kelley had developed a very intensive nutritional approach to cancer that came under harsh public scrutiny and media attention when he agreed to treat Steve McQueen.
For patients interested in Ketogenic diet, it is vitally important that you talk with your health-care providers, says Alice Bender, MS, RDN, AICR’s Director of Nutrition Programs. “A dietitian is best positioned to talk with you about what is known regarding the pros and cons – especially to learn if this diet has any research showing the reasonable application with your particular type of cancer and if the ketogenic diet may even be harmful for you.”
Treatment with MAD was shown to be more effective in seizure control when the MAD was started with lower carbohydrate limits (Kossoff et al., 2010). In a randomized study with 20 children with drug-resistant epilepsy, 60% of them showed fewer seizures in the first 3 months on the MAD, with 10 g/day of carbohydrate intake against 10% of reduction with 20 g/day (p = 0.03). In the same study, after 3 months, an increase in carbohydrate intake to 20 g/day, maintained seizure control and improved tolerability, suggesting that a lower carbohydrate limit is important only in the first 3 months (Kossoff et al., 2007; Kossoff and Dorward, 2008).
Though most of our cells can utilize fatty acids of all stripes via beta oxidation to create ATP energy, our central nervous system is at somewhat of a disadvantage. In fact, long chain fatty acids with 14 or more carbons, which can yield the most ATP from beta oxidation, do not cross the blood-brain barrier. However, in a state of prolonged dietary carbohydrate depletion, the liver begins converting acetyl coenzyme A into various ketone bodies, such as acetoacetate and beta hydroxy butyric acid, which easily penetrate into the brain and which can, like acetyl coenzyme A, be shunted into the citric acid cycle and then the electron transport chain, providing the brain with ATP.

Ketone bodies synthesized in the body can be easily utilized for energy production by heart, muscle tissue, and the kidneys. Ketone bodies also can cross the blood-brain barrier to provide an alternative source of energy to the brain. RBCs and the liver do not utilize ketones due to lack of mitochondria and enzyme diaphorase respectively. Ketone body production depends on several factors such as resting basal metabolic rate (BMR), body mass index (BMI), and body fat percentage. Ketone bodies produce more adenosine triphosphate in comparison to glucose, sometimes aptly called a "super fuel." One hundred grams of acetoacetate generates 9400 grams of ATP, and 100 g of beta-hydroxybutyrate yields 10,500 grams of ATP; whereas, 100 grams of glucose produces only 8,700 grams of ATP. This allows the body to maintain efficient fuel production even during a caloric deficit. Ketone bodies also decrease free radical damage and enhance antioxidant capacity.

Ketone production is the body’s natural response to very low or no carbohydrate availability. The ketogenic diet was developed to mimic the effects of fasting while still supplying adequate nutrition to maintain health. The classic ketogenic diet, developed in the early 1900s for children with epilepsy, consisted of a 3 or 4:1 ratio of fats to protein and carbohydrates combined, supplying up to 90% of the daily calories from fats.44 More recently, modified versions have emerged with similar rates of efficacy, and the wider variety of food and flexibility make the diet less arduous. Two such possible modifications are: a 1:1 and 2:1 ratios of fats to combined protein and carbohydrates and/or the addition of medium chain triglyceride (MCT) oil supplements. The medium chain fats that makeup MCTs more readily produce ketones than the long chain fats commonly found in the diet, allowing for a lower amount of total fat intake, and therefore increasing the amount of carbohydrate and protein that can be included in the diet.45
Type 1 Diabetes: Lowering carb intake and increasing fat intake is also beneficial for people with Type 1, Type 1.5 diabetes and LADA. A low carb diet can help reduce the number and severity of hypoglycemic episodes, lower HbA1c test results and minimize future diabetic complications. Learn more in The Ketogenic Diet for Type 1 Diabetes e-Book or click on the book cover.  These benefits are also possible for children with Type 1 and their parents should know that they have options.
Throughout this experiment, you should either keep to a standard LCHF ratio (75% fat, 20% protein, 5% carbs) or one with an even higher proportion of fat (such as 80% or 85% fat). On low-calorie days you’d eat less than 1000 calories with the same macro ratios. On high-calorie days, you’d eat about 1000 calories above your maintenance with the same macros.
Fanatic? Someone with T2D, a disease usually claimed to be progressive and a never ending stream of problems and medications, was REVERSED. That’s something to shout from the rooftops. The drop in medication use alone, but the big pharma companies would prefer that people’s stories of reversing (well, putting it into remission) T2D get called fanatical instead of insightful.
Jimmy Moore: Saturated fats are like butter and coconut oil, there’s actually more saturated fat in coconut oil than butter. People don’t realize that coconut oil is like 90% saturated fat, whereas butter something like 60 something. Full fat meats and cheeses, full fat dairy, real food of course is what we’re talking about here. Don’t just read labels on boxes, “Oh Jimmy said.” So, no.
Dietary choices to help prevent breast cancer There are many different causes of breast cancer, including age, genetics, and family history. There are also some factors that people can control, such as diet, smoking, and exercise. In this article, we take a look at the healthful foods that may help prevent breast cancer and also explain which foods to avoid. Read now
The Modified Atkins diet and modified ketogenic diet (sometimes called 'modified ketogenic therapy') use a high proportion of fats and a strict control of carbohydrates. These are often considered more flexible than the classical or MCT ketogenic diets, as more protein can be eaten, and approximate portion sizes may be used in place of weighed recipes.
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Thank you, Dr. Jockers. I really appreciate your reply. I was wondering if insulin resistance would make my cholesterol go up on the ketogenic diet from a total of 220 before I went on it to 378 after being on it for six months. I have always been in a healthy weight range for my height, but I have always been extremely hungry most of the time. I really got on the ketogenic diet hoping that this would be regulated after being on it for some time, but it hasn’t helped that much. Would this signify that insulin resistance may be the culprit for my sudden rise in cholesterol even though I am following the ketogenic diet perfectly?
Dr. Seyfried does include a chapter toward the book’s end entitled “Case Studies and Personal Experiences in using the Ketogenic Diet for Cancer Management.” Here, Dr. Seyfried provides a description of a pilot study, written by the investigators themselves, discussing the use of the ketogenic diet in children with inoperable brain cancer. However, the authors admit the study was intended only to evaluate the diet’s tolerability and effect on glucose metabolism as determined by PET scanning, not treatment benefit or survival.
Dietary treatments for diseases have probably been used for over 2000 years (Yuen and Sander, 2014). Fasting is the only therapeutic measure against epilepsy recorded in the Hippocratic collection. Two Parisian physicians, G Guelpa, and A Marie, recorded the first modern use of starvation as a treatment for epilepsy in 1911 (Wheless, 2008). The modern use of this form of therapy began in the early 1920s (Lima et al., 2014; Yuen and Sander, 2014), when Drs. Stanley Cobb and W.G. Lennox of Harvard at Harvard Medical School observed the effects of starvation as a treatment for epilepsy, noting that seizure improvement typically occurred after 2–3 days (Wheless, 2008). In the same period, Dr. Russel M. Wilder a physician at the Mayo Clinic in Minnesota, suggested that a specific diet could produce similar benefits to fasting, and proposed a diet that produced ketonemia. He studied a series of patients with epilepsy and demonstrated a result equivalent to fasting and that was maintained for a much longer period. This new concept of diet was designated the “KD.” Peterman, also at the Mayo Clinic, described a composition of the KD similar to that used today (Wilder, 1921).
In fact, a lot of people suffer from low levels of HDL cholesterol, which prevents their body from clearing out cholesterol from the blood. Most Americans don’t have enough HDL to decrease their risk of cardiovascular disease[ix]. Crazy enough, low cholesterol levels are actually associated with increased mortality from stroke and heart disease[x].
For most people, the keto diet will result in weight loss, but this might not be the healthiest way to do it. When your body burns fat because it is starved of carbs, it makes ketones. Ketones are a type of acid made by your liver and then sent into your bloodstream. Too many ketones can led to dehydration and alter the chemical balance of your blood.
That's why I co-wrote the "Fat for Fuel Ketogenic Cookbook" alongside renowned Australian celebrity chef Pete Evans. This book combines research-backed medical advice with delicious, kitchen-tested recipes that will help make shifting to fat-burning much easier. Whether you're just a budding cook or a master chef, there's a delicious meal waiting to be prepared that'll take your health to the next level.
This week we’re getting stricter with our fasting. We had a full week of intermittent fasting and now we’re going to skip breakfast and lunch. Water is our BEST friend here! Don’t forget that you can drink coffee, tea, flavored water, and the like to get your liquids in. Keep drinking to make sure you’re not thinking about your stomach. It MIGHT start growling, just ignore it – your body will adjust with time.
Seyfried agrees that there is clear evidence that cancer is a genetic disease, since we can inherit mutations that are clearly associated with increased cancer risk. That’s not at all controversial. That’s well established, and even Seyfried agrees with that. But he argues that many of these mutations that we can inherit are mutations that actually disturb cellular respiration, maybe that the heritable aspect of cancer is not mutation that drives itself—cellular proliferation—but instead are mutations that actually cause mitochondrial dysfunction and defects in cellular respiration. He also points out that many of the non-inherited causes of cancer that have been identified and are clearly recognized, like radiation, impair mitochondrial function. That may be a common mechanism that is shared between these non-inherited causes of cancer and inherited causes of cancer.

There are some treatment centers like Care Oncology Clinic in the UK and ChemoThermia Oncology Center in Istanbul that are using ketogenic diet and fasting along with glucose inhibitors and conventional treatment like chemo. They claim to be getting good results, but I don’t know much about these cancer centers above and beyond what I just told you. Note that keto only seems to work with the faster-growing cancers like breast cancer, but not as much with slower-growing cancers like prostate cancer.
This is so important. I think people need to know just because you lower your LDL doesn’t mean you’ve necessarily made yourself healthier. What it does when you have the vegetable oils and you lower your LDLC, you could see your total cholesterol go to 150 for example. Okay, you think you’ve done something good, what you’ve done though is you totally eliminated all of those healthy pattern A, the large fluffy kind, you’ve totally eliminated those drinking these vegetable oils because you’ve oxidized the LDL, making them into more of those small LDL and you’re at great risk for heart disease.
In my monograph One Man Alone, I included a case report of a patient treated by Kelley, diagnosed with an inoperable and very aggressive form of brain cancer that had spread into the spinal canal. After failing radiation, the patient began treatment with Dr. Kelley in 1981. At the time, the patient’s wife actually had to administer the treatment, even the coffee enemas, since the patient himself was largely incoherent and wheelchair bound.
Health Impact News has published many articles about the low-carb high-fat ketogenic diet, and its favorable influences on several diseases or dysfunctional health conditions. The ketogenic diet was originally developed at Johns Hopkins Hospital in the 1920s to stop seizures in children with epilepsy, when pharmaceutical drugs did not work. More recently, the ketogenic diet has been used successfully for neurological disorders such as Alzheimer's disease. Recently, there have been efforts by some researchers and medical practitioners to explore the potential of ameliorating schizophrenia, a major brain disorder that affects one out of a hundred, with the aid of the ketogenic diet.
Mitochondria generate reactive oxygen species (ROS) during their metabolic activities. In normal cells, the production of ROS and their elimination by antioxidants are kept in balance.10 Intriguingly, a higher incidence of errors, or mutations, in mitochondrial DNA have been observed in many human cancers, likely as a result of uncontrolled ROS production and oxidative stress.11
Similar results were reported by a telemedical guided weight loss program among 200 overweight adults, where triglyceride and HDL-cholesterol levels were lower at month 6 in the keto diet group compared to the low-fat group. The conclusion was that a low-carb diet has more benefits in reducing cardiovascular risks compared to the low-fat diet (12).
But in Dr. Price’s day, many groups living in many different locations still lived according to tradition largely untouched by modern Western influence. Price’s travels took him from the Eskimos of the Arctic, to the descendents of the Incas living in the high Andes, to the Masai on the plains of Kenya, to isolated Swiss herders in the Alpine mountain valleys, to Polynesians living on pristine tropical islands.
May this letter find you and your loved ones happy and healthy for without you I would not be in such an improved state of physical health? It is not often I get to put pencil to paper for not only could I not concentrate due to opiate pharmaceuticals (couldn't express oneself due to lack of cognitive thinking) but the pain, inability to get comfortable due to lymphodemia and anxiety from stress (from lack of cash flow for food, bills, medicines plus the high expense of bandages & ointments) have prevented me from making contact but ....still after this prolonged period of time, I feel it necessary to write personally to mention just how dramatically you changed the world my two children and I live in. My sister Casey Lee Smith, arrived 6 months ago from the USA to run my household and it is through "Phoenix Tears" website she was able to make contact with you and learn all about the many wondrous benefits of medicinal Cannabis oil. When the treatment arrived, I was overwhelmed for I am a single Mother and your generosity brought tears to my eyes (even now it is hard to fight tears as I write) It has been rough to say the least. Feeling helpless, overly tired and frustrated by the lack of qualified physicians in my local town. I became depressed. My ex-husband felt he should prepare the kids for my untimely death. The location of my cancer spread throughout my left quadrant into my lymph and into the brain. I became bed ridden and lost hope. I will lose my house shortly but now i know it won't be my life. So, "THANK YOU" for the gracious gift and know you are loved! Sending love to you forever and always.

We’re going full on fats with breakfast, just like we did last week. This time we’ll double the amount of ketoproof coffee (or tea) we drink, meaning we double the amount of coconut oil, butter, and heavy cream. It should come to quite a lot of calories, and should definitely keep us full all the way to dinner. Remember to continue drinking water like a fiend to make sure you’re staying hydrated.


Cholesterol serves a number of important roles in the body. First of all, cholesterol is a critical structural element in certain tissues such as our brain and nervous system. In fact, it is estimated that around 25% of our cholesterol can be found in the brain. Just to highlight our failed fat philosophy over the years, higher saturated fat intake and high cholesterol levels are associated with better mental function in old age (1)!

More research is needed to determine whether the kind of extreme carb restriction associated with keto diets is necessary to unlock all these benefits, especially if you’re healthy. “Ketogenic and other very-low-carbohydrate diets can be quite challenging to follow over the long term, and the possibility of adverse effects has not been ruled out,” says Dr. David Ludwig, a professor of nutrition at Harvard School of Public Health. “Usually, such severe restriction isn’t necessary.” He points out that not all carbs are equal, and that the speed with which a carbohydrate food affects your blood sugar—what’s known as its glycemic index—makes a difference.

If you participate in exercise that involves explosive movements such as jiujitsu, mixed martial arts, CrossFit, or even some rigorous forms of dance, you may benefit from a moderate carbohydrate intake rather than a ketogenic diet. Explosive movements draw on your muscles’ glycolytic capacity, which is powered by glucose from dietary carbohydrates. Endurance athletes, on the other hand, may thrive on a ketogenic diet because their respective activities can be adequately fueled by fatty acid oxidation and ketones.
There are numerous benefits that come with being on keto: from weight loss and increased energy levels to therapeutic medical applications. Most anyone can safely benefit from eating a low-carb, high-fat diet. Below, you’ll find a short list of the benefits you can receive from a ketogenic diet. For a more comprehensive list, you can also read our in-depth article here >
Research has indicated that a ketogenic diet raises the stress hormone cortisol to increase energy levels in the face of reduced carbohydrate availability. However, it is still up for debate whether this increase in cortisol is harmful or innocuous. Nonetheless, I recommend taking extra care to manage your stress while on a ketogenic diet. Getting plenty of sleep, exercising, and engaging in a regular stress-reduction practice can help you keep your baseline stress levels low and reduce the potential for chronically elevated cortisol.
A well-formulated ketogenic diet, besides limiting carbohydrates, also limits protein intake moderately to less than 1g/lb body weight, unless individuals are performing heavy exercise involving weight training when the protein intake can be increased to 1.5g/lb body weight. This is to prevent the endogenous production of glucose in the body via gluconeogenesis. However, it does not restrict fat or overall daily calories. People on a ketogenic diet initially experience rapid weight loss up to 10 lbs in 2 weeks or less. This diet has a diuretic effect, and some early weight loss is due to water weight loss followed by a fat loss. Interestingly with this diet plan, lean body muscle is largely spared. As a nutritional ketosis state sustains, hunger pangs subside, and an overall reduction in caloric intake helps to further weight loss.
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