In 2012, Dr. Thomas Seyfried, a PhD basic science researcher, published the book, Cancer as a Metabolic Disease, announcing to the world that a high-fat, no carbohydrate ketogenic diet represents the solution to cancer prevention as well as to cancer treatment. His monograph has been greeted with much acclaim, though not yet at the level reached at the height of the interleukin-2 hysteria in 1985.
People claiming huge benefits of these supplements – despite the lack of solid scientific support – may sometimes have a financial reason to believe in the supplements. Some of these products are sold under a multi-level marketing arrangement, where sales people are paid based on commission. For example, the company Prüvit sells drinkable ketones, called KETO//OS with a multi-level marketing structure.
Leanne: For those of you guys who don’t know Jimmy Moore, first of all you’ve probably been living under a rock because this guy’s huge. Excited to have you here on the show today. Jimmy busted on health scene in 2004 after a phenomenal 180 pound weight loss that enabled him to come off of his prescription drugs for high cholesterol, high blood pressure, and respiratory problems. He is the co-author of Cholesterol Clarity, Keto Clarity, and the energetic personality behind the blog Living La Vida Low Carb at www.livinlavidalowcarb.com, and the voice of the top ranked podcast The Livin’ La Vida Low Carb show. He’s interviewed over 900 of the world’s top health experts, I’m pretty sure I’ve listed to at least 400 of those.
In its strictest form, the ketogenic diet provides more than 90 percent of its calories through fat (as compared to the 25 to 40 percent usually recommended for children). When we burn fat for energy, rather than glucose from carbohydrates, we produce compounds known as ketone bodies—hence the name “ketogenic diet.” The increase in ketones—referred to as ketosis—is thought to have an anticonvulsant effect in the brain, although how this works is still something of a mystery.
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I have lost 20lbs, feel great, but feel deprived since this diet is so prohibitive of many fruits and vegetables. Not only that, my ldl is high! My Dr. recommended Avorstatin (20 mg). I will continue with a sensible eating routine – a small portion of foods and, yes, I will take the cholesterol med and see how the LDL measures in 6 months. I walk 10,000 steps or more daily and drink 2 bottles of water.
To counteract these genetic vulnerabilities, it is may be best to eat a low to moderate fat diet that is whole food based with plenty of fiber, monounsaturated fats, polyunsaturated fats (especially omega 3s), and limited saturated fats. This, as well as a lifestyle filled with physical activity, stress relief practices, and plenty of sleep, should keep their cholesterol levels under control.
The vast majority of claims regarding the ketogenic diet and cancer are drawn from lab and animal studies. Findings from animal studies are revealing. A study published in July’s Nature found that in mice, the ketogenic diet enhanced the effects of a specific cancer treatment. The drugs in that treatment targeted a signaling network guided by an enzyme (abbreviated P13K), which is commonly mutated in cancers.
You want to keep your cheats to none. Be prepared, make sure you’re eating what you need to be satiated (“full”), and make sure you’re satisfied with what you’re eating. If you have to force yourself to eat something, it will never work out in the end. This is just a guideline on how you can eat on a ketogenic diet, so you’re very welcome to change up what kind of foods you eat!
People suffering from diabetes and taking insulin or oral hypoglycemic agents suffer severe hypoglycemia if the medications are not appropriately adjusted before initiating this diet. The ketogenic diet is contraindicated in patients with pancreatitis, liver failure, disorders of fat metabolism, primary carnitine deficiency, carnitine palmitoyltransferase deficiency, carnitine translocase deficiency, porphyrias, or pyruvate kinase deficiency. People on a ketogenic diet rarely can have a false positive breath alcohol test. Due to ketonemia, acetone in the body can sometimes be reduced to isopropanol by hepatic alcohol dehydrogenase which can give a false positive alcohol breath test result.